Thiamine Deficiency and Brain Swelling
Clinical Study Title: Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients.
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English Summary: |
Brain
swelling, or encephalopathy, is a serious side effect
of many diseases, including renal disease. The direct
cause is often unknown, but a thiamine deficiency
is suspected. This study looked at the link between
thiamine deficiency and the risk of brain swelling
in patients with renal disease. Many of these patients
had abnormalities in their brain at the beginning
of the study. These patients were given thiamine supplements
to compensate. In all but one of these patients, the
thiamine supplementation corrected the brain swelling
and the symptoms alleviated completely. This suggests
that for diseases such as renal disease which put
patients at risk for encephalopathy, a thiamine supplements
should be administered. |
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Authors:
Hung SC. Hung SH. Tarng DC. Yang WC. Chen TW. Huang TP.
Institution:
Department of Medicine, Division of Nephrology, TaipeiVeterans General
Hospital, Taiwan.
Country of Publication:
United States
Source:
American Journal of Kidney Diseases. 38(5):941-7, 2001 Nov.
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