Vitamin B12 reduces Risk of Heart Disease
Clinical Study Title:
Improved vascular endothelial function after oral B vitamins: An
effect mediated through reduced concentrations of free plasma homocysteine.
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English Summary: |
There
are many risk factors for coronary heart disease,
including high levels of homocysteine in the blood.
B-vitamin supplementation has been shown to reduce
homocysteine levels in the blood. This study looks
at the use of vitamin b12 and folic acid to reduce
the overall risk of coronary heart disease. A total
of 89 males with coronary heart disease were enrolled
in the study and given daily supplements of folic
acid with vitamin b12 or a placebo. After 2 months
of treatment, the blood levels and heart functions
were measured again. The participants taking the vitamin
combo of folic acid and vitamin b12 had lower homocysteine
levels, which led to improved heart functioning. This
supports the use of a daily vitamin supplementation
including folic acid and vitamin b12 and may result
in a reduced risk of coronary heart disease. |
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Authors:
Chambers JC. Ueland PM. Obeid OA. Wrigley J. Refsum H. Kooner JS.
Institution:
National Heart and Lung Institute, Imperial College School of Medicine,
Hammersmith Hospital, London, UK.
Country of Publication:
United States
Source:
Circulation. 102(20):2479-83, 2000 Nov 14.
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