Vitamin B6 to Correct Anemia
Clinical Study Title:
Late-onset X-linked sideroblastic anemia following hemodialysis.
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English Summary: |
This
was a case study of an elderly patient who had been
undergoing hemodialysis and developed sideroblastic
anemia during the course of treatment. This is often
a disorder that is X-linked and can be caused by deficiencies
of various nutrients. The patient in this case was
given oral supplements of vitamin b6, and her siderbasts
were completely eliminated following this treatment.
Further analysis into the condition showed a mutation
in the gene, which altered the ability of the amino
acid to respond, and accounted for the ability of
the vitamin b6 to correct this disorder. This suggests
that various deficiencies can bring forth the sideroblastic
anemia, and that supplementation of vitamins can help
to avoid this disorder, and to treat it, especially
for patients who may be at risk for contracting it.
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Authors:
Furuyama K. Harigae H. Kinoshita C. Shimada T. Miyaoka K. Kanda
C. Maruyama Y. Shibahara S. Sassa S.
Institution:
Department of Molecular Biology and Applied Physiology, Tohoku University
School of Medicine, Sendai, Japan.
Country of Publication:
United States
Source:
Blood. 101(11):4623-4, 2003 Jun 1.
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