Protecting DNA Breakage with Vitamin E
Clinical Study Title:
Assessment of DNA strand breakage by the alkaline COMET assay in
dialysis patients and the role of Vitamin E supplementation.
| Plain
English Summary: |
Many
patients who have chronic renal failure are treated
with regular dialysis. Many of these patients become
uremic during treatment, and there is some evidence
that oxidative stress is related to this condition.
This study looked at the use of multivitamins in this
condition. A total of 36 participants who were currently
being treated with dialysis were given vitamin E supplements
daily for 2 weeks. The vitamin E was found to have
a protective effect against DNA breakage. This suggests
that vitamin E supplements may be able to help protect
against some of the complications of dialysis. |
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Authors:
Kan E. Unde?er U. Bali M. Ba?aran N.
Institution:
Department of Internal Medicine, Faculty of Medicine, Gazi University,
Ankara, Turkey.
Country of Publication:
Netherlands
Source:
Mutation Research. 520(1-2):151-9, 2002 Sep 26.
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