Vitamin K as a Supplement to Warfarin
Clinical Study Title:
Randomized, placebo-controlled trial of oral phytonadione for excessive
anticoagulation.
| Plain
English Summary: |
This
study looked at the most effective way to treat anticoagulation
associated with warfarin. A total of 30 participants
with international normalized ratios (INR) that were
above the norm were enrolled in this study. They were
given either a vitamin K supplement or a placebo.
Correction of the INR was achieved first in the group
receiving the vitamin K supplement. The use of vitamin
K as a supplement to warfarin therapy was more effective
at reducing INR than just stopping the use of warfarin
alone. This suggests always using a vitamin K supplement
whenever using warfarin. |
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Authors:
Patel RJ. Witt DM. Saseen JJ. Tillman DJ. Wilkinson DS.
Institution:
Department of Clinical Pharmacy, Kaiser Permanente, Denver, Colorado,
USA.
Country of Publication:
United States
Source:
Pharmacotherapy. 20(10):1159-66, 2000 Oct.
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