Vitamin K Reduces Warfarin Side Effects
Clinical Study Title:
Comparing different routes and doses of phytonadione for reversing
excessive anticoagulation.
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English Summary: |
The
use of warfarin often causes anticoagulation, and
this study looked at the use of vitamin K supplements
to alleviate this condition. Various other studies
that involved using vitamin K to correct the anticoagulation
were reviewed. The various methods were compared to
determine which ones were effective. The IV form of
vitamin K administration appeared to be the most effective,
but in many cases, the treatment was too much, and
many adverse reactions occurred. This suggests that
the lower dosage of IV and the oral supplements had
the most effect with the least amount of adverse reactions.
Vitamin K supplements were found to be effective in
aiding in reducing the negative effects of warfarin.
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Authors:
Whitling AM. Bussey HI. Lyons RM.
Institution:
Division of Pharmacotherapy, University of Texas Health Science
Center
Country of Publication:
United States
Source:
Archives of Internal Medicine. 158(19):2136-40, 1998 Oct 26.
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