Vitamin B3 Has Positive Effects on Asthma
Clinical Study Title:
Intravenous nicorandil prevents thiamylal-fentanyl-induced bronchoconstriction
in humans.
| Plain
English Summary: |
Research
in animals has shown that nicorandil, or vitamin B3,
has positive effects on asthma and a bronchorelaxant
effect. This effect had not been seen in humans. This
study attempted to find if nicorandil has a similar
effect on humans. Thirty-six people were given either
nicorandil or a placebo during the study. Measurements
were then taken in the airway and lung activity of
all the participants. Those participants in the nicorandil
group did have improved airway functioning, and similar
results to those of animals was seen. This suggests
that nicorandil does have a positive effect on the
bronchodilation in humans. |
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Authors:
Wajima Z. Yoshikawa T. Ogura A. Imanaga K. Shiga T. Inoue T. Ogawa
R.
Institution:
Department of Anesthesia, Chiba Hokusoh Hospital, Nippon Medical
School, Inba-gun, Japan.
Country of Publication:
United States
Source:
Critical Care Medicine. 31(2):485-90, 2003 Feb.
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