Clinical Study Title:
Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial.

Plain English Summary:

This study looked at nicorandil and its effect on cardiac events for adults who had a history of angina. Over 5100 adults were divided into 2 groups, and given either nicorandil or a placebo. Participants were followed and coronary events were measured and compared between groups. Those participants in the nicorandil group had less incidence of death due to heart disease, as well as less acute coronary syndromes. The use of nicorandil for patients with angina can help improve outcomes and the syndrome itself. Vitamin B3 supplementation is then a good treatment to help alleviate problems due to angina.

Authors

The IONA Study group.

Institution

The IONA Study group.

Country of Publication

England

Source

Lancet. 359(9314):1269-75, 2002 Apr 13.