Vitamin B6 Reduces Homocysteine Levels
Clinical Study Title:
Treatment of hyperhomocysteinemia in renal transplant recipients.
A randomized, placebo-controlled trial.
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English Summary: |
Many
patients who have undergone kidney transplants often
suffer from elevated levels of homocysteine. Elevated
levels of homocysteine is often associated with arteriosclerosis
as well as other forms of heart disease. This study
looked at the use of vitamin b6 alone against folic
acid with vitamin b12 to help reduce the homocysteine
levels. Pariticipants were placed into one of four
groups: vitamin b6 alone, folic acid and vitamin b12,
vitamin b6 with b12 and folic acid, or a placebo.
The levels of homocysteine in the blood were measured
and compared across groups. All participants except
those taking the placebo had a reduction in the homocysteine
levels. This suggests that adding vitamin b6 as a
daily supplement can have an added benefit to reducing
the homocysteine levels, especially for renal transplant
patients. |
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Authors:
Bostom AG. Gohh RY. Beaulieu AJ. Nadeau MR. Hume AL. Jacques PF.
Selhub J. Rosenberg IH.
Institution:
Jean Mayer USDA Human Nutrition Research Center, Boston, Massachusetts,
USA.
Country of Publication:
United States
Source:
Annals of Internal Medicine. 127(12):1089-92, 1997 Dec 15.
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