Clinical Study Title:
Short-term effect of vitamin K administration on prednisolone-induced loss of bone mineral density in patients with chronic glomerulonephritis.

Plain English Summary:

This study examined the use of vitamin K to help improve bone formation and help to reduce bone mineral density loss. Participants in this study all had glomerulonephritis and were taking prednisolone. Ten participants continued to take the prednisolone alone, and the other ten participants were given additional daily supplements of vitamin K. The bone mineral density of all patients was measured before, during and after the study. Those participants who were taking the additional vitamin D supplements during the study had less bone mineral density loss than the other participants who were taking prednisolone alone. This suggests that vitamin D can be a beneficial supplement to treating arthritis.

Authors

Yonemura K. Kimura M. Miyaji T. Hishida A.

Institution

Hemodialysis Unit, Hamamatsu University School of Medicine, Japan.

Country of Publication

United States

Source

Calcified Tissue International. 66(2):123-8, 2000 Feb.