Clinical Study Title:
Effect of vitamin K1 supplementation on vitamin K status in cystic fibrosis patients.

Plain English Summary:

People with cystic fibrosis are at risk for several other health problems, including a deficiency of vitamin K. This study looked at the utility of a vitamin K supplement for individuals with cystic fibrosis. Half of the participants were given supplements of vitamin K for a month, while the other participants had no supplements for a month. The supplementation was then switched, so participants who were getting supplements now were not, and those who had not gotten any, now were receiving supplements. The absorption of the vitamin K was examined at the beginning of the study, after one month and then again at 2 months. While taking the supplements, all participants had higher absorption of vitamin K as compared to when not taking the supplements. This also suggests that it is important for patients with cystic fibrosis to supplement their diet with a daily supplement of vitamin K.

Authors

Beker LT. Ahrens RA. Fink RJ. O'Brien ME. Davidson KW. Sokoll LJ. Sadowski JA.

Institution

Children's National Medical Center, Department of Pulmonary Medicine

Country of Publication

United States

Source

Journal of Pediatric Gastroenterology & Nutrition. 24(5):512-7, 1997 May.