Clinical Study Title:
Beneficial effects of nicorandil versus enalapril in chronic rheumatic severe mitral regurgitation: six months follow up echocardiographic study.

Plain English Summary:

This study compared the use of nicroandil versus enalapril for the left ventricle functioning in patients with chronic rheumatic severe mitral regurgitation. A total of 80 people participated in this study, and were given ECGs at the beginning and at the end of the 6 month study. Both the group who was given nicorandil and enalapril had reductions in the systolic volume of the left ventricle; however the group taking nicrandil had improved reductions. This suggests that the use of nicorandil, or vitamin B3, is at least equal to the drug enalapril, if not a better alternative for patients with chronic rheumatic severe mitral regurgitation in terms of cholesterol reduction.

Authors

Gupta DK. Kapoor A. Garg N. Tewari S. Sinha N.

Institution

Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Country of Publication

United States

Source

Journal of Heart Valve Disease. 10(2):158-65, 2001 Mar.