Clinical Study Title:
Pantothenic acid, coenzyme A, and human chronic ulcerative and granulomatous colitis.
|Plain English Summary:|
|This study examined vitamin B5 deficiency and the development of chronic ulcerative granulomatous colitis. A sample of tissue from the colon was taken from 29 patients who were already having a colectomy. These tissues samples were compared with colon tissues from healthy individuals. In patients with colitis, the coenzyme A level was significantly low. This suggests that there is a problem in the metabolism of the vitamin in patients with chronic ulcerative granulomatous. There is a relationship then between lower levels of vitamin B5 in the body and the development of chronic ulcerative granulomatous colitis.|