Clinical Study Title:
Low-dose oral vitamin K reliably reverses over-anticoagulation due to warfarin.

Plain English Summary:

The use of warfarin can have many adverse reactions including abnormalities with their international normalized ratio. The purpose of this study was to examine the use of a vitamin K supplement to help adjust the international normalized ratio for patients taking warfarin. All of the participants who received the vitamin K supplement had reduced levels of international normalized ratio beginning almost right after treatment. This suggests that the use of vitamin K is a safe, effective, inexpensive way to help to correct the side effects of warfarin by reducing raised levels of international normalized ratio.

Authors

Crowther MA. Donovan D. Harrison L. McGinnis J. Ginsberg J.

Institution

Hamilton Civic Hospitals Research Centre, Henderson General Hospital

Country of Publication

Germany

Source

Thrombosis & Haemostasis. 79(6):1116-8, 1998 Jun.